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Naoki Yoshimura Selected Research

Ischemia

12/2023Impaired nitric oxide mechanisms underlying lower urinary tract dysfunction in aging rats.
10/2022Therapeutic effects of a soluble guanylate cyclase activator, BAY 60-2770, on lower urinary tract dysfunction in mice with spinal cord injury.
12/2021Effects of low-dose insulin or a soluble guanylate cyclase activator on lower urinary tract dysfunction in streptozotocin-induced diabetic rats.
11/2020Effects of a new β3-adrenoceptor agonist, vibegron, on neurogenic bladder dysfunction and remodeling in mice with spinal cord injury.
1/2020[Effects of alpha-1A/D adrenoceptor antagonist and phosphodiesterase type 5 inhibitor on bladder remodeling in rats with spinal cord injury].
8/2017Effects of an alpha1A/D-adrenoceptor antagonist, naftopidil, and a phosphodiesterase type 5 inhibitor, tadalafil, on urinary bladder remodeling in rats with spinal cord injury.

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Naoki Yoshimura Research Topics

Disease

42Inflammation (Inflammations)
12/2023 - 01/2002
39Spinal Cord Injuries (Spinal Cord Injury)
03/2024 - 11/2002
28Overactive Urinary Bladder (Overactive Bladder)
01/2023 - 11/2002
28Interstitial Cystitis (Interstitial Cystitis, Chronic)
03/2022 - 01/2002
26Pain (Aches)
01/2023 - 01/2002
23Stress Urinary Incontinence
01/2020 - 12/2003
20Ulcerative Colitis
12/2023 - 01/2003
20Cystitis
01/2022 - 05/2002
16Sneezing
01/2020 - 08/2003
10Hemorrhage
01/2023 - 06/2010
9Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
10/2022 - 04/2006
9Neoplasms (Cancer)
01/2022 - 01/2002
9Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2021 - 10/2005
8Heart Failure
01/2023 - 10/2005
8Underactive Urinary Bladder
01/2022 - 01/2014
8Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2022 - 10/2005
8Ataxia (Dyssynergia)
01/2021 - 01/2004
8Crohn Disease (Crohn's Disease)
01/2021 - 08/2014
7Fibrosis (Cirrhosis)
12/2022 - 08/2017
6Ischemia
12/2023 - 08/2017
6Congenital Heart Defects (Congenital Heart Defect)
09/2023 - 05/2003
6Neurogenic Urinary Bladder (Bladder, Neurogenic)
11/2020 - 08/2003
6Wounds and Injuries (Trauma)
11/2017 - 10/2007
5Infections
12/2023 - 03/2004
5Body Weight (Weight, Body)
01/2023 - 06/2003
5Hypertrophy
10/2022 - 10/2006
5Hypersensitivity (Allergy)
01/2019 - 07/2009
5Abnormal Reflex (Hyperreflexia)
09/2011 - 11/2002
4Urinary Bladder Neoplasms (Bladder Cancer)
12/2023 - 07/2006
4Lower Urinary Tract Symptoms
01/2023 - 11/2006
4Neuralgia (Stump Neuralgia)
03/2021 - 01/2016
4Parkinson Disease (Parkinson's Disease)
05/2016 - 08/2003
4Urinary Bladder Diseases (Bladder Diseases)
01/2014 - 05/2004
4Ventricular Heart Septal Defects (Ventricular Septal Defect)
12/2006 - 12/2002
3Aneurysm (Aneurysms)
12/2023 - 10/2021
3Pulmonary Arterial Hypertension
09/2023 - 06/2011
3Urinary Retention
01/2023 - 10/2004
3Hypoxia (Hypoxemia)
10/2022 - 01/2020
3Diabetes Mellitus
12/2021 - 09/2002

Drug/Important Bio-Agent (IBA)

20Messenger RNA (mRNA)IBA
12/2023 - 10/2007
19Nerve Growth Factor (NGF)IBA
07/2023 - 09/2002
17Capsaicin (Zostrix)FDA Link
02/2024 - 11/2002
15CytokinesIBA
11/2023 - 10/2005
13Proteins (Proteins, Gene)FDA Link
11/2023 - 01/2002
13Therapeutic UsesIBA
07/2023 - 02/2008
12Cyclophosphamide (Cytoxan)FDA LinkGeneric
04/2015 - 05/2004
10Type A Botulinum Toxins (Botox)FDA Link
01/2023 - 10/2004
10salicylhydroxamic acid (SHAM)IBA
01/2017 - 09/2005
9Formaldehyde (Formol)FDA Link
01/2021 - 04/2014
7Biomarkers (Surrogate Marker)IBA
11/2023 - 02/2009
7Muscarinic AntagonistsIBA
01/2023 - 02/2005
7Adrenergic Receptors (Adrenergic Receptor)IBA
01/2020 - 02/2007
6Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2023 - 02/2005
6CollagenIBA
10/2022 - 08/2017
6Liposomes (Liposome)IBA
12/2021 - 01/2014
6Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2021 - 01/2017
6Tadalafil (Cialis)FDA Link
01/2020 - 10/2014
6ProstaglandinsIBA
11/2019 - 02/2006
6Botulinum Toxins (Botulinum Toxin)IBA
02/2017 - 11/2002
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2024 - 10/2005
5Interleukin-6 (Interleukin 6)IBA
11/2023 - 04/2014
5Cadherins (E-Cadherin)IBA
01/2022 - 01/2019
5Infliximab (Remicade)FDA Link
01/2021 - 05/2013
5Cholinergic Antagonists (Anticholinergics)IBA
01/2017 - 01/2003
5Acetic Acid (Vinegar)FDA LinkGeneric
12/2016 - 09/2002
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2016 - 09/2004
5Urethane (Ethyl Carbamate)IBA
09/2015 - 08/2003
5EnzymesIBA
03/2015 - 01/2002
4ChemokinesIBA
11/2023 - 09/2010
4SolutionsIBA
01/2023 - 01/2021
4SteroidsIBA
12/2022 - 04/2004
4Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2022 - 05/2002
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2022 - 05/2003
4Antisense OligonucleotidesIBA
12/2021 - 08/2013
4Adalimumab (Humira)FDA Link
01/2021 - 11/2016
4Cholinergic Agents (Cholinergics)IBA
01/2021 - 03/2008
4Phosphodiesterase 5 InhibitorsIBA
01/2020 - 08/2017
42-mercaptopurineIBA
09/2019 - 05/2013
4suplatast tosilateIBA
01/2019 - 05/2002
4resiniferatoxinIBA
01/2018 - 01/2003
4Norepinephrine (Noradrenaline)FDA LinkGeneric
09/2015 - 02/2007
3AcidsIBA
03/2024 - 05/2009
3Interleukin-18 (Interleukin 18)IBA
11/2023 - 01/2015
3Adrenal Cortex Hormones (Corticosteroids)IBA
12/2022 - 04/2004
3Soluble Guanylyl CyclaseIBA
10/2022 - 01/2020
3Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
01/2022 - 01/2014
3Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2022 - 08/2008
3ElastinIBA
11/2020 - 08/2017
3Streptozocin (Streptozotocin)FDA Link
05/2020 - 09/2002

Therapy/Procedure

49Therapeutics
12/2023 - 05/2002
9Cardiopulmonary Bypass (Heart-Lung Bypass)
03/2024 - 01/2002
9Intravesical Administration
01/2022 - 02/2005
8Drug Therapy (Chemotherapy)
07/2021 - 12/2003
7Thoracotomy
03/2021 - 01/2009
7Blood Component Removal (Apheresis)
11/2020 - 01/2003
5Anesthesia
03/2022 - 12/2006
5Catheters
01/2018 - 08/2003
4Ligation
07/2021 - 05/2008
3Stents
12/2023 - 12/2003
3Conservative Treatment
08/2020 - 02/2017